The current administration is pursuing policies to reduce regulations and expenditures across government agencies including at HHS, the FDA, CMS and related agencies. Recent actions include…directing HHS and other agencies to lower prescription drug costs through a variety of initiatives, including by improving upon the Medicare Drug Price Negotiation Program and establishing Most-Favored-Nation pricing for pharmaceutical products…These actions and policies may significantly reduce U.S. drug prices, potentially impacting manufacturers’ global pricing strategies and profitability, while increasing their operational costs and compliance risks.
All entries for: Lyell Immunopharma
November 12, 2025
Lyell Immunopharma
Negative Outlook
South San Francisco, California
201-500 employees
Further, the sale of pharmaceutical products overseas at lower prices than in the United States could adversely impact our U.S. pricing strategy and financial condition if the contemplated U.S. federal health care program Most-Favored-Nation pricing proposal is ultimately adopted. As a result of such policy, we may elect not to expand our business to certain foreign countries, which would limit our market opportunity.
April 8, 2025
Lyell Immunopharma
Layoffs
South San Francisco, California
201-500 employees
Five months after acquiring the cell therapy company ImmPACT Bio, Lyell Immunopharma has disclosed that it is shutting down the Los Angeles manufacturing facility that was part of the deal and letting go of 73 people at the site. The layoffs are effective June 2, according to a Worker Adjustment and Retraining Notification Act (WARN) notice.
Disease Area: Oncology
Drug Type: Biologic