Takeda’s recently announced reorganization may affect approximately 634 U.S. employees, including 247 in Cambridge, Massachusetts effective July 1, 2026, through Dec. 31, 2027, and 387 in other states, though the total could change as staff pursue redeployment opportunities.
All entries for: Takeda
March 26, 2026
Takeda
Layoffs
Cambridge, MA
50,001+ employees
Takeda has announced a significant restructuring to streamline corporate functions and generate more than $1.25 billion in savings by fiscal year 2028, though the full workforce impact has not yet been disclosed.
Disease Area: Multiple
Drug Type: Biologic, Small Molecule
January 19, 2026
Takeda
Layoffs
Cambridge, MA
50,001+ employees
Takeda is laying off 243 employees across its U.S. operations, an effort that will heavily affect its neuroscience commercialization teams.The spokesperson told the media outlet the workforce reduction was part of a “strategic decision” to help the company navigate its upcoming loss of exclusivity for Trintellix, a major depressive disorder drug. That decision also includes “reprioritizing resources to prepare for multiple potential new medication launches in the U.S.”
Disease Area: Multiple
Drug Type: Biologic, Small Molecule
October 3, 2025
Takeda
Layoffs
Cambridge, MA
50,001+ employees
Takeda is laying off 137 employees. According to an Oct. 1 Worker Adjustment and Retraining Notification (WARN) Act notice, those staffers, located in Cambridge, Massachusetts, are being let go effective Jan. 1 through July 31, 2026.
Disease Area: Multiple
Drug Type: Biologic, Small Molecule
February 5, 2025
Takeda - Cambridge
Discontinued Research
Cambridge, MA
50,001+ employees
The clinical trial titled “A Study of TAK-951 in Participants With Cyclic Vomiting Syndrome (CVS)” (NCT06768658), sponsored by Takeda, was terminated due to business reasons before enrolling any participants. Specific details regarding these business reasons were not disclosed.
1 Discontinued Research Program
Disease Area: Chronic Disease
Drug Type: Small Molecule
October 21, 2024
Takeda
Layoffs
Cambridge, MA
50,001+ employees
“Takeda is laying off dozens of employees in Massachusetts, according to a Worker Adjustment and Retraining Notification (WARN) alert filed with the state late last week. The layoff process kicked off in late September and will run through March of next year, according to state records.
“While the WARN alert states that 79 employees across the two sites are set to face cuts, the final number “is not clear at this time” and will depend on potential “redeployment opportunities,” according to a detailed filing cited by Boston Business Journal.”
Disease Area: Multiple
Drug Type: Biologic, Small Molecule
March 31, 2024
Takeda
Negative Outlook
Cambridge, MA
50,001+ employees
“We expect the IRA to negatively impact sales and profits and may lead to further political pressure, or legislative, regulatory, or other efforts to introduce lower prices reduce spending on the Medicare and Medicaid programs expand and strengthen the affordable care act and lower, the overall spending by the government and prescription medicines. In addition, various state legislature and regulators have an acted or pursuing policy changes that could further increase pricing pressure on our products as a result we expect the healthcare industry in the US will continue to be subject to increase pricing and spending pressure.”
Disease Area: Multiple
Drug Type: Biologic, Small Molecule