All entries for: Chronic Disease

October 31, 2024

Alnylam

Discontinued Drug, Discontinued Research

Cambridge, MA
1,001-5,000 employees
1001-5000 employees

“Today announced the decision to suspend further clinical development of ALN-KHK, an investigational RNAi therapeutic targeting ketohexokinase for the treatment of type 2 diabetes mellitus. This decision reflects portfolio prioritization efforts to allocate clinical, managerial and financial resources carefully to bring transformative medicines to patients.”

1 Discontinued Drug: ALN-KHK (biologic)
1 Discontinued Research Program

Disease Area: Chronic Disease
Drug Type: Biologic
April 24, 2024

BioMarin

Discontinued Drug, Discontinued Research, Layoffs

San Rafael, CA
1,001-5,000 employees
1001-5000 employees

As a result of its prioritized portfolio, four programs will be discontinued, including BMN 331, BMN 255, BMN 355 and BMN 365. None of the programs were discontinued due to safety signals.

4 Discontinued Drugs: BMN 331 (biologic), BMN 255 (biologic), BMN 355 (biologic), BMN 365 (biologic)
4 Discontinued Research Programs

Disease Area: Cardiology, Chronic Disease, Multiple, Rare Diseases
Drug Type: Biologic
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