All entries for: Oncology

March 26, 2026

Biodexa Pharmaceuticals Plc

Negative Outlook

Cardiff, UK
1-50 employees

In August 2022, the Inflation Reduction Act, or IRA, was signed into the law the IRA. The IRA includes multiple provisions that may impact the prices of drug products that are both sold into the Medicare program and throughout the United States. For example, a manufacturer of a drug or biological product covered by Medicare Parts B or D must pay a rebate to the federal government if the product’s price increases faster than the rate of inflation. This calculation is made on a product-by-product basis and the amount of the rebate owed to the federal government is directly dependent on the volume of a drug product that is paid for by Medicare Parts B or D. Additionally, CMS will negotiate drug prices annually for a select number of single source Part D drugs without generic or biosimilar competition. CMS will also negotiate drug prices for a select number of Part B drugs starting for payment year 2028. If a drug product is selected by CMS for negotiation, it is expected that the revenue generated from such drug will decrease.

Disease Area: Neurological Diseases, Oncology
Drug Type: Small Molecule
March 26, 2026

Galapagos NV

Neutral Outlook

Mechelen, Belgium
1,001-5,000 employees

The effects of the IRA on our business and the healthcare industry in general is not yet known.

Disease Area: Immune Diseases, Oncology
Drug Type: Small Molecule
March 26, 2026

Can-Fite BioPharma Ltd

Neutral Outlook

Petah Tikva, Israel
1-50 employees

On August 16, 2022, President Biden signed the Inflation Reduction Act of 2022, which includes several provisions to lower prescription drug costs for people with Medicare, including price negotiation requirements for drugs covered under Medicare, rebate requirements when drug prices rise faster than inflation, and a cap on out-of-pocket spending for Medicare Part D enrollees.

Disease Area: Immune Diseases, Oncology
Drug Type: Small Molecule
March 26, 2026

Zentalis Pharmaceuticals, Inc

Neutral Outlook

San Diego, CA
51-200 employees

While the impact of the IRA on the pharmaceutical industry cannot yet be fully determined, it is likely to be significant.

Disease Area: Oncology
Drug Type: Small Molecule
March 26, 2026

Actuate Therapeutics, Inc

Neutral Outlook

Fort Worth, TX
1-50 employees

It is currently unclear how the IRA will be implemented but it is likely to have a significant impact on the pharmaceutical industry.

Disease Area: Oncology
Drug Type: Small Molecule
March 25, 2026

Atossa Therapeutics, Inc.

Negative Outlook

Seattle, WA
1-50 employees

The taxes imposed by any new federal legislation and the expansion in government’s effect on the U.S. healthcare industry, including the Inflation Reduction Act enacted in August 2022, may result in decreased profits to us, lower reimbursements by payors for our products or reduced medical procedure volumes, all of which may adversely affect our business, financial condition and results of operations.

Disease Area: Oncology
Drug Type: Small Molecule
March 25, 2026

Nkarta, Inc.

Neutral Outlook

South San Francisco, California
51-200 employees

The effect of the IRA on our business and the healthcare industry in general is not yet known, but we continue to evaluate its potential impact.

Disease Area: Oncology
Drug Type: Biologic
March 25, 2026

BeyondSpring

Neutral Outlook

Florham Park, NJ
51-200 employees

For example, the Inflation Reduction Act of 2022, or IRA, enacted on August 16, 2022, seeks to reduce prescription drug costs by, among other provisions, allowing Medicare to negotiate prices for certain high-cost prescription drugs in Medicare Parts B and D, imposing an excise tax on pharmaceutical manufacturers that refuse to negotiate pricing with Medicare, requiring inflation rebates to limit annual drug price increases in Medicare, and redesigning the Medicare Part D formula.

Disease Area: Hematology, Oncology
Drug Type: Small Molecule
March 24, 2026

Absci Corp/WA

Neutral Outlook

Vancouver, WA
201-500 employees

The IRA also enacted significant changes intended to reduce prescription drug spending and beneficiary out-of-pocket costs, including redesigning the Medicare Part D benefit beginning in 2025 (including a lower annual out-of-pocket threshold), replacing the prior coverage gap discount framework with a new Part D Manufacturer Discount Program, requiring inflation-based rebates in certain contexts, and establishing a Medicare Drug Price Negotiation Program that permits CMS to set a “maximum fair price” for certain qualifying single-source drugs and biologics reimbursed under Medicare Part B and/or Part D.

Disease Area: Immune Diseases, Oncology
Drug Type: Biologic
March 24, 2026

Curis Inc/MA

Neutral Outlook

Lexington, MA
51-200 employees

Further, with the passage of the Inflation Reduction Act, or the IRA, in August 2022, Congress extended the expansion of PPACA premium tax credits through 2025.

Disease Area: Hematology, Oncology
Drug Type: Small Molecule
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