In addition, recent legislative and regulatory proposals in the United States have included “most favored nation”, or MFN, drug pricing policies designed to align the prices in the U.S. with the lower prices in other countries. If enacted, this could affect profitability for any of our drug candidates that obtain marketing approval in the U.S., if any, as well as in other countries, as a price referencing policy to the U.S. market could make it commercially unviable to launch in a price constrained market.