Incubate’s Investment Tracker measures the impacts of the Inflation Reduction Act’s healthcare provisions on the life sciences ecosystem, with special attention to the impacts of the small molecule penalty.

Date
Date
Disease Area
Drug Type
Announcement Type
Company Size
March 8, 2026

Mahzi Therapeutics

Orphan Drug Designation

treatment of Pitt Hopkins syndrome

Disease Area: Rare Disease
March 8, 2026

OcuNeo Therapeutics Inc.

Orphan Drug Designation

Sioux Falls
1-50 employees

treatment of vernal keratoconjunctivitis

Disease Area: Rare Disease
March 6, 2026

GENFIT

Orphan Drug Designation

treatment of acute-on-chronic liver failure

Disease Area: Rare Disease
March 6, 2026

Aminex Therapeutics, Inc.

Orphan Drug Designation

Kenmore
1-50 employees

prevention of allograft rejection in liver transplantation

Disease Area: Rare Disease
March 5, 2026

Aminex Therapeutics, Inc.

Orphan Drug Designation

Kenmore
1-50 employees

treatment of malignant glioma

Disease Area: Rare Disease
March 5, 2026

Multitude Therapeutics Inc.

Orphan Drug Designation

Shanghai
1-50 employees

treatment of malignant glioma

Disease Area: Rare Disease
March 5, 2026

Multitude Therapeutics Inc.

Orphan Drug Designation

Shanghai
1-50 employees

treatment of soft tissue sarcoma

Disease Area: Rare Disease
March 5, 2026

RNR Biomedical inc

Orphan Drug Designation

Tenafly
1-50 employees

treatment of Behcet disease

Disease Area: Rare Disease
March 2, 2026

Shanghai Allovanta Biotechnology Co., Ltd.

Orphan Drug Designation

Shanghai
1-50 employees

treatment of follicular lymphoma

Disease Area: Rare Disease
March 2, 2026

Takeda Development Center Americas, Inc.

Orphan Drug Designation

Cambridge
1-50 employees

treatment of narcolepsy type 1

Disease Area: Rare Disease
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