All entries for: Small Molecule

February 5, 2025

Takeda

Discontinued Research

Cambridge, MA
10,001-50,000 employees

The clinical trial titled “A Study of TAK-951 in Participants With Cyclic Vomiting Syndrome (CVS)” (NCT06768658), sponsored by Takeda, was terminated due to business reasons before enrolling any participants. Specific details regarding these business reasons were not disclosed.

1 Discontinued Research Program

Disease Area: Chronic Disease
Drug Type: Small Molecule
February 5, 2025

X4 Pharmaceuticals

Layoffs

Boston, MA
51-200 employees

43 employees laid off. All pre-clinical programs paused.

Disease Area: Rare Diseases
Drug Type: Biologic, Small Molecule
February 4, 2025

Bristol Myers Squibb

Layoffs

Princeton, NJ
10,001-50,000 employees

67 employees laid off in New Jersey.

Disease Area: Rare Diseases
Drug Type: Biologic, Small Molecule
February 3, 2025

Omega Therapeutics

Layoffs

Cambridge, MA
51-200 employees

Laying off up to 17 employees.

Drug Type: Biologic, Small Molecule
February 3, 2025

Viracta Therapeutics

Layoffs

Cardiff, CA
1-50 employees

Company closed and laid off all staff.

Disease Area: Rare Diseases
Drug Type: Biologic, Small Molecule
January 28, 2025

I-Mab

Layoffs

Rockville, MD
201-500 employees

27% reduction in workforce.

Disease Area: Rare Diseases
Drug Type: Biologic, Small Molecule
January 27, 2025

Allakos

Layoffs

51-200 employees

75% reduction in workforce.

Disease Area: Rare Diseases
Drug Type: Biologic, Small Molecule
January 22, 2025

Biogen

Layoffs

Cambridge, MA
5,001-10,000 employees

Laying off an undisclosed number of employees.

Disease Area: Rare Diseases
Drug Type: Biologic, Small Molecule
January 15, 2025

University of Rochester Medical Center

Discontinued Research

Rochester, NY
1-50 employees

The APATIT-G study was a pilot clinical trial conducted by the University of Rochester to evaluate the safety and effectiveness of avatrombopag in treating thrombocytopenia caused by temozolomide in glioma patients. However, the study was terminated by the sponsor before it could be completed.

1 Discontinued Research Program

Disease Area: Oncology
Drug Type: Small Molecule
January 13, 2025

Apellis

Layoffs

Waltham, MA
501-1,000 employees

Laying off about 40 non-U.S. employees.

Disease Area: Rare Diseases
Drug Type: Biologic, Small Molecule
Scroll to Top