Pfizer will part ways with more than 200 employees across Switzerland as part of a continuing effort to slow its cash burn, according to a report from Bloomberg on Dec. 10. After the layoffs, the pharma expects its Switzerland headcount to shrink to around 70 people, down from 300, the publication noted, citing anonymous sources familiar with the matter.
All entries for: Home
November 25, 2025
Novartis
Layoffs
Basel, Switzerland
10,001-50,000 employees
Novartis will cut 550 full-time jobs at a facility in Switzerland by the end of 2027. The cuts come as the pharma company is ending production of tablets, capsules, and sterile medicine packaging at a plant in Stein, Switzerland.
Disease Area: Cardiology, Hematology, Immune Diseases, Multiple, Oncology
Drug Type: Biologic, Small Molecule
November 20, 2025
Ensoma
Layoffs
Boston, MA
51-200 employees
As it transitions into a clinical-stage company, genetic therapy startup Ensoma is leaving behind half of its employees. CEO Jim Burns confirmed to Endpoints News that only 37 workers will remain with the company.
Disease Area: Rare Diseases
Drug Type: Biologic
November 20, 2025
AbbVie
Layoffs
North Chicago, IL
50,001+ employees
AbbVie is laying off 59 employees across three California sites, effective Jan. 9, according to a Worker Adjustment and Retraining Notification (WARN) Act notice filed Nov. 13. AbbVie will permanently close the Dublin and Livermore sites after Jan. 9.
Disease Area: Oncology
Drug Type: Biologic
November 19, 2025
CERO THERAPEUTICS HOLDINGS, INC.
Negative Outlook
South San Francisco, California
1-50 employees
For example, the Medicare Drug Price Negotiation Program, administered by CMS as part of the Inflation Reduction Act of 2022, commonly referred to as the IRA, may apply to our products if they are selected for negotiation, which could materially reduce the amount of revenue we can generate from our products if they are approved.
Disease Area: Oncology
Drug Type: Biologic
November 19, 2025
AbbVie
Discontinued Research
North Chicago, IL
50,001+ employees
AbbVie has decided to call it quits with Google’s Calico Life Sciences. The move will involve layoffs affecting around 100 chemists. AbbVie will use the saved money to fund its biologics and cell and RNA therapies.
Disease Area: Oncology
Drug Type: Biologic
November 18, 2025
Merck
Layoffs
Rahway, NJ
10,001-50,000 employees
Merck is letting go of 204 employees from its Rahway, New Jersey location, continuing its aggressive layoff spree in recent months.
Disease Area: Antiviral, Cardiology, Immune Diseases, Multiple, Neurological Diseases, Oncology
Drug Type: Biologic, Small Molecule
November 17, 2025
Bristol Myers Squibb
Layoffs
Lawrenceville, NJ
10,001-50,000 employees
Bristol Myers Squibb has announced another round of layoffs, affecting 110 employees at the Lawrence Township site.
Disease Area: Cardiology, Hematology, Immune Diseases, Neurological Diseases, Oncology
Drug Type: Biologic, Small Molecule
November 14, 2025
IO Biotech, Inc.
Neutral Outlook
Boston, MA
51-200 employees
For example, the Inflation Reduction Act (the “IRA”), which was passed in 2022, imposes inflation rebates on drug manufacturers for products reimbursed under Medicare Parts B and D if the prices of those products increase faster than inflation; and, beginning in 2026, the IRA establishes a “maximum fair price” for a fixed number of high expenditures pharmaceutical and biological products covered under Medicare Parts B and D following a price negotiation process with CMS. Similar efforts to control pharmaceutical and biological product pricing are also taking place at the state level.
Disease Area: Oncology
Drug Type: Biologic